You are viewing an incomplete version of our website. Please click to reload the website as full version.

NFKB2 antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (p49/p100)) (N-Term)

Details for Product anti-NFKB2 Antibody No. ABIN182649, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms NF-kappaB2, lyt, p49, p49/p100, p50B, p52
Epitope
N-Term
(17), (17), (14), (13), (9), (6), (5), (5), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(135), (62), (36), (2), (1), (1), (1)
Host
Rabbit
(141), (10)
Clonality
Polyclonal
Conjugate
This NFKB2 antibody is un-conjugated
(7), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(118), (47), (37), (35), (30), (23), (12), (11), (5), (4), (4), (1), (1), (1), (1)
Pubmed 2 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 50 μg
Options
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human NFKB2
Blocking Peptide Blocking peptide for this product available: ABIN980670
Sequence LPGASSEKGR KTYPTVKICN YEGPAKIEVD LVTHSDPPRA HAHSLVGKQC
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against NFKB2. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name NFKB2 (NFKB2 Antibody Abstract)
Background NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-kappa-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-kappa-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
Molecular Weight 101 kDa
Gene ID 4791
NCBI Accession NP_002493, NM_002502
UniProt Q00653
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 933 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-NFKB2 antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (p49/p100)) (N-Term) (ABIN182649) WB Suggested Anti-NFKB2 Antibody Titration: 0.2-1 ug/ml
Positive Control...
Immunohistochemistry (IHC) image for anti-NFKB2 antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (p49/p100)) (N-Term) (ABIN182649) anti-Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 2 (p49/p100) (NFKB2) (N-Term) antibody (Image 2)
Product cited in: Suen, Uddin, Prow et al.: "Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits." in: Virology, Vol. 494, pp. 1-14, 2016 (PubMed).

Background publications Xiao, Fong, Sun: "Induction of p100 processing by NF-kappaB-inducing kinase involves docking IkappaB kinase alpha (IKKalpha) to p100 and IKKalpha-mediated phosphorylation." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30099-105, 2004 (PubMed).

Catalog No. ABIN182649
$289.00
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)
Did you look for something else?