PHKG2 antibody (N-Term)

Catalog No. ABIN182739

This anti-PHKG2 antibody is a Rabbit Polyclonal antibody detecting PHKG2 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Rabbit, Sheep and Zebrafish (Danio rerio).

Quick Overview for PHKG2 antibody (N-Term) (ABIN182739)

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Goat, Guinea Pig, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHKG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PHKG2 Antibody

Binding Specificity: N-Term

Sequence: EDELPDWAAA KEFYQKYDPK DVIGRGVSSV VRRCVHRATG HEFAVKIMEV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PHKG2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHKG2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 406 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHKG2

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Alternative Name: PHKG2

Background: Mutations in PHKG2 along with PHKA2 and PHKB, all three different genes of phosphorylase kinase (Phk) subunits, can give rise to glycogen storage disease of the liver. The autosomal-recessive, liver-specific variant of Phk deficiency is caused by mutations in the gene encoding the testis/liver isoform of the catalytic gamma subunit, PHKG2.
Alias Symbols: GSD9C
Protein Interaction Partner: HAUS2, VCP, TP53, CDKN1A, UBC, PRKDC, PHKA2, PHKA1, ATAD3C, DRG1, NDUFA4, TNPO1, FASN, ACACA, GCN1L1, YME1L1, STUB1, SCO2, NPEPPS, VDAC2, ZC3H15, ATAD3A, BZW2, UBE3A, PHKG1,
Protein Size: 406

Molecular Weight: 46 kDa

Gene ID: 5261

NCBI Accession: NM_000294, NP_000285

UniProt: P15735

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process