PHKG2 antibody (N-Term)

Catalog No. ABIN2777737

Product Details anti-PHKG2 Antibody

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Sheep, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHKG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EDELPDWAAA KEFYQKYDPK DVIGRGVSSV VRRCVHRATG HEFAVKIMEV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PHKG2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PHKG2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 406 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PHKG2

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Alternative Name: PHKG2 (PHKG2 Products)

Synonyms: PHKG2 antibody, MGC145608 antibody, zgc:55863 antibody, GSD9C antibody, 1500017I02Rik antibody, phosphorylase kinase catalytic subunit gamma 2 antibody, phosphorylase kinase, gamma 2 (testis) antibody, phosphorylase kinase, gamma 2 (testis) L homeolog antibody, PHKG2 antibody, phkg2 antibody, phkg2.L antibody, Phkg2 antibody

Background: Mutations in PHKG2 along with PHKA2 and PHKB, all three different genes of phosphorylase kinase (Phk) subunits, can give rise to glycogen storage disease of the liver. The autosomal-recessive, liver-specific variant of Phk deficiency is caused by mutations in the gene encoding the testis/liver isoform of the catalytic gamma subunit, PHKG2.
Alias Symbols: GSD9C
Protein Interaction Partner: HAUS2, VCP, TP53, CDKN1A, UBC, PRKDC, PHKA2, PHKA1, ATAD3C, DRG1, NDUFA4, TNPO1, FASN, ACACA, GCN1L1, YME1L1, STUB1, SCO2, NPEPPS, VDAC2, ZC3H15, ATAD3A, BZW2, UBE3A, PHKG1,
Protein Size: 406

Molecular Weight: 46 kDa

Gene ID: 5261

NCBI Accession: NM_000294, NP_000285

UniProt: P15735

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process