Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (N-Term) antibody

Details for Product No. ABIN182956
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Antigen
Synonyms ASH2L, ash2-like, ASH2, ASH2L1, ASH2L2, Bre2, fb34c06, fe38b04, fi20h02, wu:fb34c06, wu:fe38b04, wu:fi20h02, zgc:171444
Epitope
N-Term
(5), (4), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Rat (Rattus), Dog (Canine), Human
(35), (8), (7), (3), (2), (2), (1), (1)
Host
Rabbit
(30), (6)
Clonality
Polyclonal
Application
Western Blotting (WB)
(35), (9), (8), (7), (4), (4), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN182956
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Immunogen Synthetic peptide directed towards the N terminal of human ASH2L
Sequence EPSSGEAEGG EANLVDVSGG LETESSNGKD TLEGAGDTSE VMDTQAGSVD
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Rat : 100 %, Mouse : 90 %
Characteristics This is a rabbit polyclonal antibody against ASH2L. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name ASH2L
Background ASH2L plays a role in hematopoiesis and is associated with some special kinds of leukemia. The amount of ASH2L transcripts is extremely high in fetal liver, testis, and leukemia cell lines with erythroid and megakaryocytic potential.
Molecular Weight 69 kDa
Gene ID 9070
NCBI Accession NP_004665, NM_004674
UniProt Q9UBL3
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 628 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (N-Term) antibody anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (N-Term) antibody
Background publications Yokoyama, Wang, Wysocka et al.: "Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression." in: Molecular and cellular biology, Vol. 24, Issue 13, pp. 5639-49, 2004 (PubMed).

Validation Images
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