ASH2L Products
(Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))
Categories
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis (By similarity).
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Featured ASH2L Categories
ASH2L Antibodies
High quality antibodies with extensive validation data.
ASH2L Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ASH2L Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (7)
Cat. No.
ABIN5542582
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
Cat. No.
ABIN7270266
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (5)
Cat. No.
ABIN7169424
Quantity
100 μg
Datasheet
Datasheet
Recommended ASH2L Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345852
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345854
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7125072
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ASH2L products
: "PKA-binding domain of AKAP8 is essential for direct interaction with DPY30 protein." in: The FEBS journal, Vol. 285, Issue 5, pp. 947-964, (2019) (PubMed).: "Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases." in: The Journal of biological chemistry, Vol. 287, Issue 33, pp. 27275-89, (2012) (PubMed).
: "Multiple histone methyl and acetyltransferase complex components bind the HLA-DRA gene." in: PLoS ONE, Vol. 7, Issue 5, pp. e37554, (2012) (PubMed).
: "NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters." in: PLoS ONE, Vol. 6, Issue 3, pp. e17220, (2011) (PubMed).
: "Role of PTIP in class switch recombination and long-range chromatin interactions at the immunoglobulin heavy chain locus." in: Molecular and cellular biology, Vol. 31, Issue 7, pp. 1503-11, (2011) (PubMed).
: "An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain." in: PLoS ONE, Vol. 5, Issue 11, pp. e14102, (2010) (PubMed).
: "The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation." in: Development (Cambridge, England), Vol. 137, Issue 6, pp. 935-43, (2010) (PubMed).
: "Ash2l interacts with Tbx1 and is required during early embryogenesis." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 5, pp. 569-76, (2010) (PubMed).
: "RARγ is required for correct deposition and removal of Suz12 and H2A.Z in embryonic stem cells." in: Journal of cellular physiology, Vol. 226, Issue 2, pp. 293-8, (2010) (PubMed).
: "CXXC finger protein 1 contains redundant functional domains that support embryonic stem cell cytosine methylation, histone methylation, and differentiation." in: Molecular and cellular biology, Vol. 29, Issue 14, pp. 3817-31, (2009) (PubMed).
Synonyms and alternative names related to ASH2L
ASH2 like histone lysine methyltransferase complex subunit (ASH2L), ash2 (absent, small, or homeotic)-like (Drosophila) (Ash2l), ash2 (absent, small, or homeotic)-like (Drosophila) (ash2l), ash2 (absent, small, or homeotic)-like L homeolog (ash2l.L), ASH2 like histone lysine methyltransferase complex subunit (Ash2l), ASH2, ash2-like, ASH2L, ASH2L1, ASH2L2, Bre2, fb34c06, fe38b04, fi20h02, wu:fb34c06, wu:fe38b04, wu:fi20h02, zgc:171444Protein level used designations for ASH2L
- ASH2-like protein
- set1/Ash2 histone methyltransferase complex subunit ASH2
- ash2-like
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