DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (N-Term) antibody

Details for Product No. ABIN183041
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Antigen
Synonyms DCP1A, 1110066A22Rik, 4930568L04Rik, AU019772, D14Ertd817e, Mitc1, SMIF, RGD1561298, mitc1, HSA275986, Nbla00360, SMAD4IP1, smad4ip1, smif
Epitope
N-Term
(9), (7), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Human
(64), (30), (15), (13), (13), (12), (1), (1), (1)
Host
Rabbit
(47), (11), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(53), (31), (10), (6), (5), (4), (3), (2), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN183041
229.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human DCP1A
Sequence EEMPSGSQDK SAPSGHKHLT VEELFGTSLP KEQPAVVGLD SEEMERLPGD
Predicted Reactivity Bovine : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Horse : 90 %
Characteristics This is a rabbit polyclonal antibody against DCP1A. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name DCP1A
Background Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.
Molecular Weight 56 kDa
Gene ID 55802
NCBI Accession NP_060873, NM_018403
UniProt Q9NPI6
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 515 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A) (N-Term) antibody WB Suggested Anti-DCP1A Antibody Titration: 2.5ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
Background publications Lehner, Sanderson: "A protein interaction framework for human mRNA degradation." in: Genome research, Vol. 14, Issue 7, pp. 1315-23, 2004 (PubMed).

Validation Images
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