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Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4) (N-Term) antibody

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Antigen
Synonyms ACCN4, BNAC4, Accn4, Spasic
Epitope
N-Term
(20), (16), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus)
(49), (21), (21), (2)
Host
Rabbit
(49)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(36), (21), (11), (4), (3), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human ACCN4
Blocking Peptide Blocking peptide for this product available: ABIN972804
Sequence SPSSRGQMPI EIVCKIKFAE EDAKPKEKEA GDEQSLLGAV APGAAPRDLA
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against ACCN4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ACCN4 (ACCN4 Antibody Abstract)
Background ACCN4 belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. ACCN4 is predominantly expressed in the pituitary gland, and might be a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder.
Molecular Weight 46 kDa
Gene ID 55515
NCBI Accession NM_182847
Research Area Neurology
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 417 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4) (N-Term) antibody (ABIN183191) WB Suggested Anti-ACCN4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Amiloride-Sensitive Cation Channel 4, Pituitary (ACCN4) (N-Term) antibody (ABIN183191) WB Suggested Anti-ACCN4
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.00
Background publications Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Catalog No. ABIN183191
$289.00
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