Vestigial Like 1 (Drosophila) (VGLL1) (N-Term) antibody

Details for Product No. ABIN183247
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Antigen
Synonyms RGD1564038, VGLL1, vgl1, TDU, VGL1, Tondu
Epitope
N-Term
(3), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(24), (2)
Host
Rabbit
(20), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(16), (10), (4), (3), (3), (3), (2)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN183247
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Immunogen Synthetic peptide directed towards the N terminal of human VGLL1
Sequence LFTYFQGDIS SVVDEHFSRA LSNIKSPQEL TPSSQSEGVM LKNDDSMSPN
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against VGLL1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Protein A purified
Alternative Name VGLL1
Background VGLL1 is a specific coactivator for the mammalian TEFs. The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA-binding domain. In Drosophila, Scalloped (Sd) interacts with Vestigial (Vg) to form a complex, which binds DNA through the Sd TEA/ATTS domain. The Sd-Vg heterodimer is a key regulator of wing development, which directly controls several target genes and is able to induce wing outgrowth when ectopically expressed.
Molecular Weight 29 kDa
Gene ID 51442
NCBI Accession NP_057351, NM_016267
UniProt Q99990
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 258 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Vestigial Like 1 (Drosophila) (VGLL1) (N-Term) antibody WB Suggested Anti-VGLL1 Antibody Titration: 2.5ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
Background publications Vaudin, Delanoue, Davidson et al.: "TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation." in: Development (Cambridge, England), Vol. 126, Issue 21, pp. 4807-16, 1999 (PubMed).

Validation Images
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