PSMB8 antibody (AA 52-276)

Catalog No. ABIN1833779

Product Details anti-PSMB8 Antibody

Target: PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))

Binding Specificity: AA 52-276

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Human LMP7 / PSMB8

Purification: Immunoaffinity purified

Immunogen: Recombinant fragment corresponding to a region within amino acids 52 and 276 of PSMB8 (SwissProt P28062). Percent identity by BLAST analysis: Human (100%), Mouse, Pig, Rat (94%), Bovine (93%), Dog (91%), Xenopus (83%), Zebrafish (82%).

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: ICC (1:100 - 1:1000), IHC, IHC-P (1:100 - 1:1000), WB (1:500 - 1:3000)

Usage: IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (  pH 6.0) or Tris-EDTA buffer (  pH 8.0).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.0, 20 % glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Keep as concentrated solution. Avoid multiple freeze-thaw cycles.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for PSMB8

Target: PSMB8 (Proteasome (Prosome, Macropain) Subunit, beta Type, 8 (Large Multifunctional Peptidase 7) (PSMB8))

Alternative Name: PSMB8 / LMP7 (PSMB8 Products)

Synonyms: ALDD antibody, D6S216 antibody, D6S216E antibody, JMP antibody, LMP7 antibody, NKJO antibody, PSMB5i antibody, RING10 antibody, ATP6V0D2 antibody, lmp7 antibody, prosome antibody, macropain antibody, Lmp-7 antibody, Lmp7 antibody, Ring10 antibody, proteasome subunit beta 8 antibody, proteasome subunit beta 8A antibody, proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) antibody, PSMB8 antibody, psmb8a antibody, Psmb8 antibody

Background: Name/Gene ID: PSMB8
Subfamily: Threonine T1
Family: Protease Non Catalytic

Synonyms: PSMB8, D6S216, ALDD, Low molecular mass protein 7, LMP7, JMP, Proteasome subunit beta 5i, Proteasome subunit beta type-8, PSMB5i, Macropain subunit C13, Y2, NKJO, Protease component C13, Proteasome component C13, Proteasome subunit beta-5i, Proteasome-related gene 7, RING10, Beta5i, D6S216E, Low molecular weight protein 7, Proteasome subunit Y2

Gene ID: 5696

UniProt: P28062

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA