PLA2G7 antibody (AA 53-64)

Catalog No. ABIN1834030

Product Details anti-PLA2G7 Antibody

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Binding Specificity: AA 53-64

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This PLA2G7 antibody is un-conjugated

Application: ELISA

Specificity: Human LP-PLA2 / PLA2G7. Reported variants represent identical protein: NP_005075.3, NP_001161829.1

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-QTKIPRGNGPYS from an internal region of human LP-PLA2 / PLA2G7 (NP_005075.3). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Marmoset (100%), Gibbon, Pig (92%), Elephant, Panda, Cat, Bovine, Horse (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Preliminary experiments gave an approx 100kD band in Human Liver lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 50.1kD according to NP_005075.3. The 100kD band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for PLA2G7

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Alternative Name: LP-PLA2 / PLA2G7 (Lp-PLA2 Products)

Synonyms: LDL-PLA2 antibody, LP-PLA2 antibody, PAFAD antibody, PAFAH antibody, Lp-PLA2 antibody, PAF-AH antibody, R75400 antibody, zgc:77563 antibody, phospholipase A2 group VII antibody, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) antibody, PLA2G7 antibody, Pla2g7 antibody, pla2g7 antibody

Background: Name/Gene ID: PLA2G7
Family: Phospholipase

Synonyms: PLA2G7, GVIIA-PLA2, PAF acetylhydrolase, PAFAD, PAF 2-acylhydrolase, PAFAH, LDL-PLA(2), LP-PLA2, Group-VIIA phospholipase A2, LDL-PLA2

Gene ID: 7941

NCBI Accession: NP_005075

UniProt: Q13093

Pathways: Peptide Hormone Metabolism