K(lysine) Acetyltransferase 5 (KAT5) (N-Term) antibody

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Antigen
Synonyms
6121, CG6121, DmEG0007.7, Dmel/TIP60, Dmel\\CG6121, Dmel\\TIP60, EG0007.7, EG:EG0007.7, TIP60, dTIP60, dTip60, dmHAG405, im:6908768, wu:fb55b08, zgc:110752, ESA1, HTATIP, HTATIP1, PLIP, TIP, ZC2HC5, c ... show more
6121, CG6121, DmEG0007.7, Dmel/TIP60, Dmel\\CG6121, Dmel\\TIP60, EG0007.7, EG:EG0007.7, TIP60, dTIP60, dTip60, dmHAG405, im:6908768, wu:fb55b08, zgc:110752, ESA1, HTATIP, HTATIP1, PLIP, TIP, ZC2HC5, cPLA2, AI839539, CPLA2, Htatip, Htatip1, Tip55, Tip60 show less
Epitope
N-Term
(16), (16), (11), (8), (7), (7), (6), (6), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(153), (64), (45), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(132), (22)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(105), (82), (52), (20), (11), (11), (9), (6), (6), (2), (2), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human HTATIP
Sequence EGCRLPVLRR NQDNEDEWPL AEILSVKDIS GRKLFYVHYI DFNKRLDEWV
Predicted Reactivity Zebrafish : 85 %
Characteristics This is a rabbit polyclonal antibody against HTATIP. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Alternative Name HTATIP (KAT5 Antibody Abstract)
Background HTATIP belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.
Molecular Weight 62 kDa
Gene ID 10524
NCBI Accession NP_874369, NM_182710
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 546 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Immunohistochemistry (IHC) image for anti-K(lysine) Acetyltransferase 5 (KAT5) (N-Term) antibody (ABIN183712) anti-K(lysine) Acetyltransferase 5 (KAT5) (N-Term) antibody
Western Blotting (WB) image for anti-K(lysine) Acetyltransferase 5 (KAT5) (N-Term) antibody (ABIN183712) WB Suggested Anti-HTATIP
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500...
Background publications Murr, Loizou, Yang et al.: "Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks." in: Nature cell biology, Vol. 8, Issue 1, pp. 91-9, 2006 (PubMed).

Catalog No. ABIN183712
$289.00
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