HIF1AN antibody (N-Term)

Catalog No. ABIN183780

The Rabbit Polyclonal anti-HIF1AN antibody (ABIN183780) specifically detects HIF1AN in WB. The antibody is reactive with Human, Rabbit, Horse and Pig samples.

Quick Overview for HIF1AN antibody (N-Term) (ABIN183780)

Target: HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))

Reactivity: Human, Rabbit, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIF1AN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIF1AN Antibody

Binding Specificity: N-Term

Sequence: MAATAAEAVA SGSGEPREEA GALGPAWDES QLRSYSFPTR PIPRLSQSDP

Predicted Reactivity: Horse: 86%, Human: 93%, Pig: 79%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against HIF1AN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HIF1AN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 349 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HIF1AN

Target: HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))

Alternative Name: HIF1AN

Background: HIF1AN is a co-repressor that interacts with hypoxia-inducible factor 1 (HIF-1) alpha and the von Hippel-Lindau tumor suppressor protein to mediate repression of HIF-1 transcriptional activity.
Alias Symbols: FIH1
Protein Interaction Partner: HIF1A, ASB8, ASB7, ASB6, ASB5, ASB16, UACA, FEM1B, NFKB1, ASB9, UBC, UBD, HIF1AN, UBE3A, ELAVL1, OTUD7B, FBF1, ASB13, HDAC3, INVS, HDAC2, HDAC1, VHL, ASB4, SIAH1,
Protein Size: 349

Molecular Weight: 40 kDa

Gene ID: 55662

NCBI Accession: NM_017902, NP_060372

UniProt: Q9NWT6

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development