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Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) (N-Term) antibody

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Antigen
Epitope
N-Term
(17), (15), (14), (12), (11), (9), (7), (7), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(111), (41), (32), (2), (2), (2), (2), (2)
Host
Rabbit
(98), (20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(96), (56), (48), (32), (21), (11), (10), (7), (5), (4), (2), (1)
Pubmed 1 reference available
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Quantity 100 μg
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Immunogen Synthetic peptide directed towards the N terminal of human ANP32A
Sequence MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI
Predicted Reactivity Human : 100 %, Zebrafish : 90 %, Rat : 80 %, Mouse : 70 %
Characteristics This is a rabbit polyclonal antibody against ANP32A. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name ANP32A (ANP32A Antibody Abstract)
Background ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Molecular Weight 29 kDa
Gene ID 8125
NCBI Accession NP_006296, NM_006305
UniProt P39687
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 249 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) (N-Term) antibody (ABIN183895) WB Suggested Anti-ANP32A Antibody Titration: 1.25ug/ml
Positive Control:...
Immunohistochemistry (IHC) image for anti-Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) (N-Term) antibody (ABIN183895) anti-Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A) (N-Term) antibody (ABIN183895) WB Suggested Anti-ANP32A
Antibody Titration: 1.25 µg/mL
Positive Contro...
Background publications Stelzl, Worm, Lalowski et al.: "A human protein-protein interaction network: a resource for annotating the proteome. ..." in: Cell, Vol. 122, Issue 6, pp. 957-68, 2005 (PubMed).

Catalog No. ABIN183895

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