Exosome Component 10 (EXOSC10) (C-Term) antibody

Details for Product No. ABIN183903
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Antigen
Synonyms
Pmscl2, zgc:55695, pm-scl, pm/scl-100, pmscl, pmscl2, rrp6, rrp6p, EXOSC10, 201.t00018, 21.m02990, DDBDRAFT_0203581, DDBDRAFT_0233752, DDB_0203581, DDB_0233752, PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6 ... show more
Pmscl2, zgc:55695, pm-scl, pm/scl-100, pmscl, pmscl2, rrp6, rrp6p, EXOSC10, 201.t00018, 21.m02990, DDBDRAFT_0203581, DDBDRAFT_0233752, DDB_0203581, DDB_0233752, PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4 show less
Epitope
C-Term
(3), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Xenopus laevis, Human
(29), (16), (16), (13), (12), (12)
Host
Rabbit
(27), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(17), (10), (6), (5), (5), (3), (1), (1)
Pubmed 1 reference available
Quantity 100 μg
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Catalog No. ABIN183903
229.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human EXOSC10
Sequence FAGNSKSKVS SQFDPNKQTP SGKKCIAAKK IKQSVGNKSM SFPTGKSDRG
Predicted Reactivity Horse : 92 %, Dog : 82 %, Mouse : 82 %, Rabbit : 82 %, African clawed frog : 72 %, Bovine : 72 %
Characteristics This is a rabbit polyclonal antibody against EXOSC10. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name EXOSC10
Background EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.
Molecular Weight 97 kDa
Gene ID 5394
NCBI Accession NP_001001998, NM_001001998
UniProt Q01780
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 885 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Exosome Component 10 (EXOSC10) (C-Term) antibody WB Suggested Anti-EXOSC10 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysate
anti-Exosome Component 10 (EXOSC10) (C-Term) antibody (2) anti-Exosome Component 10 (EXOSC10) (C-Term) antibody (Image 2)
anti-Exosome Component 10 (EXOSC10) (C-Term) antibody (3) WB Suggested Anti-EXOSC10
Antibody Titration: 5.0 µg/mL ELISA Titer: 1:.2500
Positive Control: Jurkat cell lysate
EXOSC10 is supported by BioGPS gene expression data to be expressed in Jurkat
Background publications Lehner, Sanderson: "A protein interaction framework for human mRNA degradation." in: Genome research, Vol. 14, Issue 7, pp. 1315-23, 2004 (PubMed).

Validation Images
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