Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (N-Term) antibody

Details for Product No. ABIN183914
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Antigen
Synonyms
rnpu1z, rpu1, snrp70, u170k, u1ap, u1rnp, SNRP70, wu:fc20b04, zgc:136450, 2700022N21Rik, 3200002N22Rik, 70kDa, AI325098, R74807, Rnulp70, Snrp70, Srnp70, U1-70, U1-70K, RNPU1Z, RPU1, Snp1, U170K, U1AP ... show more
rnpu1z, rpu1, snrp70, u170k, u1ap, u1rnp, SNRP70, wu:fc20b04, zgc:136450, 2700022N21Rik, 3200002N22Rik, 70kDa, AI325098, R74807, Rnulp70, Snrp70, Srnp70, U1-70, U1-70K, RNPU1Z, RPU1, Snp1, U170K, U1AP, U1RNP show less
Epitope
N-Term
(7), (6), (3), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Xenopus laevis, Human, Zebrafish (Danio rerio)
(25), (5), (5), (3), (3), (2), (1), (1)
Host
Rabbit
(20), (4), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(22), (11), (5)
Pubmed 2 references available
Quantity 100 μg
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Catalog No. ABIN183914
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Immunogen Synthetic peptide directed towards the N terminal of human SNRP70
Sequence YLPPLEKLPH EKHHNQPYCG IAPYIREFED PRDAPPPTRA ETREERMERK
Predicted Reactivity Mouse :100 %,   Human :100 %,   Western clawed frog :100 %,   Green puffer :100 %,   Bovine :100 %,   Zebrafish :100 %,   African clawed frog :100 %,   Dog :100 %,   Rat :100 %,   Blackleg fungus :90 %,   Florida lancelet :80 %,   Black-legged tick :70 %,   Body louse :70 %,   Mosquito :70 %,   Yellowfever mosquito :70 %,   African malaria mosquito :70 %,   Red flour beetle :70 %,  
Characteristics This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot and immunohistochemistry.
Purification Protein A purified
Alternative Name SNRP70
Background SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA.
Molecular Weight 48 kDa
Gene ID 6625
NCBI Accession NM_003089, NP_003080
UniProt P08621
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 437 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (N-Term) antibody WB Suggested Anti-SNRP70 Antibody Titration: 5.0ug/ml
ELISA Titer: 1:62500
Positive Control: HepG2 cell lysate
anti-Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (N-Term) antibody (2) anti-Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (N-Term) antibody (Image 2)
anti-Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70) (N-Term) antibody (3) WB Suggested Anti-SNRP70
Antibody Titration: 5.0 µg/mL ELISA Titer: 1:.2500
Positive Control: HepG2 cell lysate
SNRNP70 is supported by BioGPS gene expression data to be expressed in HepG2
Background publications Brandenberger, Wei, Zhang et al.: "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation." in: Nature biotechnology, Vol. 22, Issue 6, pp. 707-16, 2004 (PubMed).

General Zhang, Walker, Tamplin et al.: "Zfp206 regulates ES cell gene expression and differentiation." in: Nucleic acids research, Vol. 34, Issue 17, pp. 4780-90, 2006 (PubMed).

Validation Images
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