THO Complex 3 antibody (Middle Region)

Catalog No. ABIN184069

This Rabbit Polyclonal antibody specifically detects THO Complex 3 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for THO Complex 3 antibody (Middle Region) (ABIN184069)

Target: THO Complex 3 (THOC3)

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THO Complex 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-THO Complex 3 Antibody

Binding Specificity: Middle Region

Sequence: PDGQTIAVGN KDDVVTFIDA KTHRSKAEEQ FKFEVNEISW NNDNNMFFLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against THOC3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human THOC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 351 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-THO Complex 3 antibody (ABIN184069)

Strässer, Masuda, Mason, Pfannstiel, Oppizzi, Rodriguez-Navarro, Rondón, Aguilera, Struhl, Reed, Hurt: "TREX is a conserved complex coupling transcription with messenger RNA export." in: Nature, Vol. 417, Issue 6886, pp. 304-8, (2002) (PubMed).

Target Details for THO Complex 3

Target: THO Complex 3 (THOC3)

Alternative Name: THOC3

Background: THOC3 is part of the TREX (transcription/export) complex, which includes THO2, HPR1, ALY, and UAP56.TEX1 is part of the TREX (transcription/export) complex, which includes THO2 (MIM 300395), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM].
Alias Symbols: TEX1
Protein Interaction Partner: THOC2, ALYREF, THOC5, DDX39B, SUMO2, NCBP1, UBC, MLKL, BRCA1, ZCRB1, THOC7, THOC6, ZC3H15, ZKSCAN5, THOC1, VIM, UTRN, TTC1, HDGF, TK1, YOD1,
Protein Size: 351

Molecular Weight: 39 kDa

Gene ID: 84321

NCBI Accession: NM_032361, NP_115737

UniProt: Q96J01