THO Complex 3 antibody (Middle Region)

Catalog No. ABIN2776596

This Rabbit Polyclonal antibody specifically detects THO Complex 3 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).It has been mentioned in 1 publication

Quick Overview for THO Complex 3 antibody (Middle Region) (ABIN2776596)

Target: THO Complex 3 (THOC3)

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THO Complex 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-THO Complex 3 Antibody

Binding Specificity: Middle Region

Purpose: THOC3 Antibody - middle region

Sequence: PDGQTIAVGN KDDVVTFIDA KTHRSKAEEQ FKFEVNEISW NNDNNMFFLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against THOC3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human THOC3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41052-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-THO Complex 3 antibody (ABIN2776596)

Strässer, Masuda, Mason, Pfannstiel, Oppizzi, Rodriguez-Navarro, Rondón, Aguilera, Struhl, Reed, Hurt: "TREX is a conserved complex coupling transcription with messenger RNA export." in: Nature, Vol. 417, Issue 6886, pp. 304-8, (2002) (PubMed).

Target Details for THO Complex 3

Target: THO Complex 3 (THOC3)

Alternative Name: THOC3

Background:

Targeted Subunit: 3

Background Information: THOC3 is part of the TREX (transcription/export) complex, which includes THO2, HPR1, ALY, and UAP56.TEX1 is part of the TREX (transcription/export) complex, which includes THO2 (MIM 300395), HPR1 (MIM 606930), ALY (MIM 604171), and UAP56 (MIM 606390).[supplied by OMIM].

Gene Name: THO complex 3

Alternative Symbols: THO3, hTREX45

Protein Name: THO complex subunit 3

Molecular Weight: 39kDa

Gene ID: 84321

NCBI Accession: NP_115737

UniProt: Q96J01