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THO Complex 3 antibody (AA 2-351)

THOC3 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7172051
  • Target See all THO Complex 3 (THOC3) Antibodies
    THO Complex 3 (THOC3)
    Binding Specificity
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-351
    Reactivity
    • 28
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Host
    • 25
    • 3
    Rabbit
    Clonality
    • 26
    • 2
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    This THO Complex 3 antibody is un-conjugated
    Application
    • 23
    • 19
    • 4
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human THO complex subunit 3 protein (2-351AA)
    Isotype
    IgG
    Top Product
    Discover our top product THOC3 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    THO Complex 3 (THOC3)
    Alternative Name
    THOC3 (THOC3 Products)
    Synonyms
    THOC3 antibody, zgc:100815 antibody, THO3 antibody, hTREX45 antibody, 2410044K02Rik antibody, AL033344 antibody, THO complex 3 antibody, THO complex subunit 3 antibody, THOC3 antibody, thoc3 antibody, LOC100400596 antibody, Thoc3 antibody
    Background

    Background: Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5\' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi\'s sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.

    Aliases: hTREX45 antibody, TEX1 homolog antibody, THO complex subunit 3 antibody, Tho3 antibody, THOC3 antibody, THOC3_HUMAN antibody

    UniProt
    Q96J01
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