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Details for Product No. ABIN184156

Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (C-Term) antibody

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Antigen
Synonyms AITR, CD357, GITR, GITR-D, Gitr, TNFRSF18
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN184156
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-TNFRSF18 antibody: synthetic peptide directed towards the C terminal of human TNFRSF18
Sequence LRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAE EKGRLGDLWV
Predicted Reactivity Human : 100%
Characteristics This is a rabbit polyclonal antibody against TNFRSF18. It was validated on Western Blot and immunohistochemistry. We manufacture rabbit polyclonal antibodies on a large scale of high throughput manner. Our antibodies are peptide based and protein family oriented.
Purification Affinity Purified
Alternative Name TNFRSF18
Background The protein encoded by TNFRSF18 is a member of the TNF-receptor superfamily. This receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death.
Molecular Weight 26kDa
Gene ID 8784
NCBI Accession NP_004186, NM_004195
UniProt Q9Y5U5
Research Area Immunology, Adaptive Immunity, Growth Factors, Innate Immunity, Cytokines
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-TNFRSF18 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Alternatives for antigen "Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18)", type "Antibodies"
Hosts (60), (22), (20)
Reactivities (70), (51), (13)
Applications (68), (35), (29), (10), (8), (7), (4), (2), (2), (1), (1)
Conjugates (11), (10), (8), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (1), (1)
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