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RGS10 antibody (Middle Region)

RGS10 Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN184197
  • Target See all RGS10 Antibodies
    RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
    Binding Specificity
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 27
    • 10
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
    Host
    • 25
    • 3
    Rabbit
    Clonality
    • 26
    • 2
    Polyclonal
    Conjugate
    • 21
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RGS10 antibody is un-conjugated
    Application
    • 18
    • 11
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    DQIFNLMKYD SYSRFLKSDL FLKHKRTEEE EEDLPDAQTA AKRASRIYNT
    Predicted Reactivity
    Cow: 81%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 90%, Rat: 90%
    Characteristics
    This is a rabbit polyclonal antibody against RGS10. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RGS10
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    Discover our top product RGS10 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 181 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RGS10 (Regulator of G-Protein Signaling 10 (RGS10))
    Alternative Name
    RGS10 (RGS10 Products)
    Synonyms
    MGC82511 antibody, RGS10 antibody, 2310010N19Rik antibody, regulator of G-protein signaling 10 antibody, regulator of G-protein signaling 10 L homeolog antibody, regulator of G protein signaling 10 antibody, regulator of G-protein signalling 10 antibody, RGS10 antibody, rgs10.L antibody, rgs10 antibody, Rgs10 antibody
    Background
    Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
    Protein Interaction Partner: UBC, ADRB2, APP, PRKACA, GNAI3, GNAO1, GNAI1, GNAZ, GNRHR, CALM1, ACP6, SAP18, EIF6,
    Protein Size: 181
    Molecular Weight
    21 kDa
    Gene ID
    6001
    NCBI Accession
    NM_001005339, NP_001005339
    UniProt
    Q96GN0
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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