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Details for Product No. ABIN184208

Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) (N-Term) antibody

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Antigen
Synonyms H731, Ma3, Tis, D19Ucla1, Dug, h731, MGC69337, PDCD4
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN184208
Quantity 100 µg
Price
229.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-PDCD4 antibody: synthetic peptide directed towards the N terminal of human PDCD4
Sequence MTKYPDNLSDSLFSGDEENAGTEEIKNEINGNWISASSIN EARINAKAKR
Predicted Reactivity Bovine : 100%, Dog : 100%, Goat : 100%, Guinea pig : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, Rat : 100%
Characteristics This is a rabbit polyclonal antibody against PDCD4. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Protein A purified
Alternative Name PDCD4
Background PDCD4 is a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.
Molecular Weight 52kDa
Gene ID 27250
NCBI Accession NP_055271, NM_014456
UniProt O15501
Research Area Cancer, Apoptosis/Necrosis, Transcription Factors, Signaling
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-PDCD4 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Yang, Matthews, Clair et al.: "Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion." in: Molecular and cellular biology, Vol. 26, Issue 4, pp. 1297-306, 2006 (PubMed).

Alternatives for antigen "Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4)", type "Antibodies"
Hosts (96), (20), (4)
Reactivities (125), (76), (75), (13), (6), (5), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (106), (76), (39), (35), (11), (10), (10), (5), (4), (3), (2), (2)
Conjugates (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (20), (20), (9), (8), (6), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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