c-FOS antibody (C-Term)
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- Target See all c-FOS (c-Fos) Antibodies
- c-FOS (c-Fos) (c-Fos)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Pig, Dog, Sheep
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This c-FOS antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- CTPSCTAYTS SFVFTYPEAD SFPSCAAAHR KGSSSNEPSS DSLSSPTLLA
- Cross-Reactivity
- Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against FOS. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human FOS
- Top Product
- Discover our top product c-Fos Primary Antibody
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- Application Notes
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WB Suggested Anti-FOS Antibody Titration: 1.25 µg/mL
ELISA Titer: 1:312500
Positive Control: HepG2 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator. - Comment
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Antigen size: 380 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- c-FOS (c-Fos) (c-Fos)
- Alternative Name
- C-fos (c-Fos Products)
- Synonyms
- AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
- Background
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The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
Alias Symbols: p55, AP-1, C-FOS
Protein Interaction Partner: Psma4, CENPO, LMO3, ARFGAP1, USF2, USF1, PSMC5, PRKAA2, JUNB, JUN, GNG11, NQO1, ATF2, AQP1, LUZP4, CYTH4, CREB5, ABL1, CLU, ATP5I, APP, MTERF4, ANP32E, ARL6IP4, COPS4, CABP1, ZNF133, SET, NEFM, MAP1B, JUND, HSPA1A, MAF, FOS, DDIT3, CEBPG, CEBPE, CEBPA, AT
Protein Size: 380 - Molecular Weight
- 41 kDa
- Gene ID
- 2353
- NCBI Accession
- NM_005252, NP_005243
- UniProt
- P01100
- Pathways
- S100 Proteins
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