DDIT3 antibody

Catalog No. ABIN1843159

Product Details anti-DDIT3 Antibody

Target: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDIT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)

Specificity: GADD153 Antibody detects endogenous levels of GADD153.

Purification: Immunogen affinity purified

Immunogen: A synthesized peptide derived from human GADD153.

Application Details

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage Comment: Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for DDIT3

Target: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Alternative Name: GADD153 (DDIT3 Products)

Synonyms: chop antibody, Xchop antibody, cebpz antibody, chop10 antibody, gadd153 antibody, CHOP-10 antibody, CHOP10 antibody, CHOP antibody, Chop10 antibody, Gadd153 antibody, CEBPZ antibody, GADD153 antibody, DNA damage inducible transcript 3 antibody, DNA-damage inducible transcript 3 antibody, DNA damage inducible transcript 3 L homeolog antibody, ddit3 antibody, Ddit3 antibody, DDIT3 antibody, ddit3.L antibody

Background: CHOP a transcriptional-regulatory protein of the bZIP family. Inhibits the DNA-binding activity of C/EBP and LAP by forming heterodimers that cannot bind DNA. May play an important role in melanoma progression. CK2-mediated phosphorylation inhibits its transcriptional activity. Up-regulates IL-6 transcription by trapping negative regulating NF-IL6 isoform.

Molecular Weight: 26 kDa

Pathways: Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis