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PRTN3 antibody
PRTN3
Reactivity: Human
WB, ELISA
Host: Mouse
Monoclonal
unconjugated
Product Details anti-PRTN3 Antibody
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Target
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PRTN3
(Proteinase 3 (PRTN3))
Reactivity
All reactivities for PRTN3 antibodies
Human
Host
All hosts for PRTN3 antibodies
Mouse
Clonality
All clonalities for PRTN3 antibodies
Monoclonal
Conjugate
All conjugates for PRTN3 antibodies
This PRTN3 antibody is un-conjugated
Application
All applications for PRTN3 antibodies
Western Blotting (WB), ELISA
Purification
Purified by Protein G affinity chromatography
Immunogen
Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
Isotype
IgG2b
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS containing 50 % glycerol and 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target Details for PRTN3
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Target
PRTN3
(Proteinase 3 (PRTN3))
Alternative Name
Proteinase 3 (PRTN3 Products )
Synonyms
ela2 antibody, MGC132250 antibody, ACPA antibody, AGP7 antibody, C-ANCA antibody, CANCA antibody, MBN antibody, MBT antibody, NP-4 antibody, NP4 antibody, P29 antibody, PR-3 antibody, PR3 antibody, mPR3 antibody, proteinase 3 L homeolog antibody, proteinase 3 antibody, prtn3.L antibody, PRTN3 antibody, Prtn3 antibody
Background
Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.
Molecular Weight
28 kDa
Gene ID
5657
UniProt
P24158
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