SOCS1 antibody (C-Term)

Catalog No. ABIN184575

This anti-SOCS1 antibody is a Goat Polyclonal antibody detecting SOCS1 in ELISA, IHC, IF and FACS. Suitable for Human and Mouse.

Quick Overview for SOCS1 antibody (C-Term) (ABIN184575)

Target: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This SOCS1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Verified

Product Details anti-SOCS1 Antibody

Binding Specificity: C-Term

Purpose: SOCS1

Sequence: VLRDYLSSFP FQI

Cross-Reactivity: Cow, Dog, Human, Mouse, Pig, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-VLRDYLSSFPFQI, from the C Terminus of the protein sequence according to NP_003736.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Kidney. Recommended concentration: 8 μg/mL. Paraffin embedded Mouse Kidney. Recommended concentration: 5-10 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:4000.

Comment:

Immunofluorescence: Expression of the protein seen in the cytoplasm and nucleus of MCF7 cells. Recommended concentration: 10μg/ml.

Flow Cytometry: Flow cytometric analysis of HEK293 cells. Recommended concentration: 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for SOCS1

Target: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Alternative Name: SOCS1

Background: SOCS1, JAB, CIS1, SSI1, TIP3, CISH1, Cish1, SSI-1, SOCS-1, suppressor of cytokine signaling 1, JAK binding protein, Tec-interacting protein 3, STAT induced SH3 protein 1, cytokine-inducible SH2 protein 1

Gene ID: 8651, 12703

NCBI Accession: NP_003736

Pathways: JAK-STAT Signaling, Interferon-gamma Pathway, TLR Signaling, Response to Growth Hormone Stimulus