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anti-NQO1 (Quinone reductase 1) antibody

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Antigen: NQO1 (Quinone reductase 1)
Clonality: Polyclonal
Application: ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
Reactivity: Human
Host: Goat
5 references available 5 references available
Quantity: 100 ug
Price: 498,75 $   (Plus shipping costs $25 and VAT, Invoice in EUR)
Order number: ABIN184714
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Additional Information  » anti-NQO1 (Quinone reductase 1) antibody

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Antigen NQO1 (Quinone reductase 1)
Gene ID 1728 , 18104 (mouse)
Immunogen C-SIPTDNQIKARK
Reactivity Human
Clonality Polyclonal
Format Aff - Purified
Description All names and symbols: NQO1, NAD(P)H dehydrogenase, quinone 1, DTD, QR1, DHQU, DIA4, NMOR1, NMORI, diaphorase-4, diaphorase (NADH/NADPH), diaphorase (NADH/NADPH) (cytochrome b-5 reductase), NAD(P)H:menadione oxidoreductase 1, dioxin-inducible 1. Official Symbol: NQO1. RefSeq number(s): NP_000894.1, NP_001020604.1, NP_001020605.1. Gene ontology terms: NAD(P)H dehydrogenase (quinone) activity, cytochrome b5 reductase activity, nitric oxide biosynthesis, response to toxin, synaptic transmission, cholinergic, xenobiotic metabolism, electron transport, cytoplasm, oxidoreductase activity
Host Goat
Specificity This products is expected to recognize all three reported isoforms (NP_000894.1, NP_001020604.1 and NP_001020605.1). Human, Mouse, Rat 274 aa

Application Details  » anti-NQO1 (Quinone reductase 1) antibody

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Application ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
» Click here to view 2 available protocols!
Application Notes Peptide ELISA: antibody detection limit dilution 1:64,000. Western Blot: Approx. 30kDa band observed in Human Kidney and Lung lysates (calculated MW of 30.9kDa according to NP_000894.1). Recommended concentration: 0.03-0.1µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Research Area Metabolism, Drugs
Restrictions For Research Use only

Publications  » anti-NQO1 (Quinone reductase 1) antibody

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Publications Asher, Lotem, Kama et al.: "NQO1 stabilizes p53 through a distinct pathway." In: Proceedings of the National Academy of Sciences of the United States of America , Vol. 99, Issue 5, pp. 3099-104, 2002 (PubMed)

van Horssen, Schreibelt, Boe et al.: "NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions." In: Free radical biology & medicine , Vol. 41, Issue 2, pp. 311-7, 2006 (PubMed)

Ritz, Wan, Diaz-Sanchez: "Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract." In: American journal of physiology. Lung cellular and molecular physiology , Vol. 292, Issue 1, pp. L33-9, 2007 (PubMed)

Tanaka, Aleksunes, Cui et al.: "ANIT-induced intrahepatic cholestasis alters hepatobiliary transporter expression via Nrf2-dependent and independent signaling." In: Toxicological sciences : an official journal of the Society of Toxicology , Vol. 108, Issue 2, pp. 247-57, 2009 (PubMed)

Schriner, Avanesian, Liu et al.: "Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses." In: Free radical biology & medicine , Vol. 47, Issue 5, pp. 577-84, 2009 (PubMed)