TXNRD1 antibody (C-Term)

Catalog No. ABIN184781

The Goat Polyclonal anti-TXNRD1 antibody has been validated for WB, IHC and ELISA. It is suitable to detect TXNRD1 in samples from Human.

Quick Overview for TXNRD1 antibody (C-Term) (ABIN184781)

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TXNRD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Grade: Verified

Product Details anti-TXNRD1 Antibody

Binding Specificity: C-Term

Purpose: Thioredoxin Reductase 1

Sequence: TKRSGASILQ AGC

Specificity: This antibody is expected to recognise reported isoform 1 (NP_003321.2), isoform 2 (NP_877393.1, NP_877419.1, NP_877420.1) and isoform 3 (NP_001087240.1)

Cross-Reactivity: Human

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence TKRSGASILQAGC, from the C Terminus of the protein sequence according to NP_003321.2, NP_877393.1, NP_877419.1, NP_877420.1, NP_001087240.1.

Isotype: IgG

Application Details

Application Notes:

Immunohistochemistry: Paraffin embedded Human Testis and Spleen. Recommended concentration: 2.5 μg/mL.

Western Blot: Approx 60 kDa band observed in Human Placenta lysates (predicted MW of 57 kDa according to NP_003321). Recommended for use at 0.1-1 μg/mL.

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Alternative Name: TXNRD1

Background: TXNRD1, thioredoxin reductase 1, TR1, TXNR, GRIM-12, MGC9145, TR, TRXR1, KM-102-derived reductase-like factor, oxidoreductase, thioredoxin reductase GRIM-12

Gene ID: 7296

NCBI Accession: NP_003321, NP_877393, NP_877419, NP_877420, NP_001087240

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis