C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) antibody
| Antigen |
|
| Synonyms |
MER, RP38, c-mer, MGC133349, Eyk, Mer, Nyk, rdy, C-EYK, MERTK, DKFZp469D2215, si:ch1073-268l12.2 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Conjugate
|
Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
|
|
Application
|
|
| Catalog no. |
ABIN184984 |
| Quantity |
100 ug |
| Price |
261.61 $ Plus shipping costs $45.00
|
|
Bulk discount
|
| Shipping to |
|
| Availability |
Ships within 5 Business Days |
|
Alternative name
|
MERTK
|
|
Gene ID
|
10461
|
|
Immunogen
|
C-DSSEGSEVLM
|
|
Description
|
All names and symbols: MERTK, c-mer proto-oncogene tyrosine kinase, mer, C-MER, c-mer. Official Symbol: MERTK. RefSeq number(s): NP_006334. Gene ontology terms: transmembrane receptor protein tyrosine kinase activity, ATP binding, receptor activity, cell growth and/or maintenance, vision, protein amino acid phosphorylation, cell surface receptor linked signal transduction, cell-cell signaling, soluble fraction, integral to plasma membrane, transferase activity
|
|
Specificity
|
Human
|
|
Application Notes
|
Peptide ELISA: antibody detection limit dilution 1:2000. Western Blot: Approx. 30kDa band observed in Human Brain, Human Ovary, Human Kidney, MOLT-4 and U937 lysates at 1ug of primary. Please note that the band we observe is different from the predicted size of approx. 115kDa according to NP_006334. Currently we cannot find an explanation for this in the literature. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any splice variants/modified forms been reported?
|
|
Purification
|
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
|
|
Buffer
|
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
|
|
Storage
|
Aliquot and store at -20°C. Minimize freezing and thawing.
|
|
Research Area
|
Neurology, Tyrosine Kinases
|
|
Restrictions
|
For Research Use only
|
|
|
Graham, Dawson, Mullaney et al.: "Cloning and mRNA expression analysis of a novel human protooncogene, c-mer." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 5, Issue 6, pp. 647-57, 1994 (PubMed).
|
Alternatives for antigen "C-Mer Proto-Oncogene Tyrosine Kinase (MERTK)", type "Antibodies"
|
Hosts
|
Rabbit (34), Mouse (9), Goat (2), Rat (1)
|
|
Reactivities
|
Human (43), Mouse (Murine) (19), Rat (Rattus) (18)
|
|
Applications
|
Western Blotting (WB) (28), ELISA (16), Immunofluorescence (IF) (16), Immunoprecipitation (IP) (5), Immunohistochemistry (IHC) (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunoelectron Microscopy (IEM) (1)
|
|
Conjugates
|
Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
|
|
Epitopes
|
N-Term (4), Extracellular Domain (3), AA 50-100 (2), C-Term (2), AA 200-250 (1), AA 746-757 (1), Phosphospecific (1)
|
Alternatives 
2013 BioMed Central Research Awards
