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Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8) antibody

Details for Product No. ABIN185076, Supplier: Login to see
Antigen
  • MGC81285
  • MGC146320
  • AW261790
Alternatives
anti-Human Epidermal Growth Factor Receptor Pathway Substrate 8 antibody for ELISA
Reactivity
Human, Mouse (Murine), Rat (Rattus)
69
26
23
5
3
2
2
2
1
Host
Goat
52
14
5
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
ELISA
44
37
30
12
11
7
4
3
1
1
1
Supplier
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Immunogen C-SGVESFDEGSSH
Blocking Peptide Blocking peptide for this product available: ABIN369873
Specificity Human, Mouse, Rat 822 aa
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name EPS8 (EPS8 Antibody Abstract)
Background All names and symbols: EPS8, epidermal growth factor receptor pathway substrate 8. Official Symbol: EPS8. RefSeq number(s): NP_004438. Gene ontology terms: SH3/SH2 adaptor protein, EGF receptor signaling pathway, cell proliferation, signal transduction
Gene ID 2059, 13860
Research Area Cancer, Growth Factors
Pathways EGFR Signaling Pathway
Application Notes Peptide ELISA: antibody detection limit dilution 1:8,000. Western Blot: Preliminary experiments gave no signal but low background in A431 and Hela lysates at up to 1µg/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Restrictions For Research Use only
Format Liquid
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Background publications Fazioli, Minichiello, Matoska et al.: "Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals." in: The EMBO journal, Vol. 12, Issue 10, pp. 3799-808, 1993 (PubMed).