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Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (Isoform 1) antibody

Antigen

Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)
Synonyms TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MGC1839, MGC104264
Binding Site
Alternatives

Isoform 1
Clonality Polyclonal
Host
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA, Western Blotting (WB)
1 reference available
Catalog no. ABIN185242
Quantity 100 ug
Price 374.27 $   Plus shipping costs $45.00
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anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (Isoform 1) antibody

Additional Information
Application Details Publications Images Alternatives back to top

Alternative name MCL1
Gene ID 4170, 17210 (mouse)
Immunogen C-AGVGAGLAYLIR
Description All names and symbols: MCL1, TM, EAT, MCL1L, MCL1S, MGC1839, MGC104264, myeloid cell leukemia sequence 1 (BCL2-related), induced myeloid leukemia cell differentiation protein Mcl-1, myeloid cell leukemia sequence 1, myeloid cell leukemia sequence 1, isoform 1. Official Symbol: MCL1. RefSeq number(s): NP_068779.1. Gene ontology terms: apoptotic program, heat shock response, development
Specificity This antibody is expected to recognise isoform 1 (NP_068779.1). Human, Mouse, Rat, Dog, Cat

Application Details
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Application Notes Peptide ELISA: antibody detection limit dilution 1:2,000. Western Blot: Approx 35kDa band observed in lysates of Human Lung and cell line K562 (calculated MW of 37.3kDa according to NP_068779.1). Recommended concentration: 1-3µg/ml.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Aliquot and store at -20°C. Minimize freezing and thawing.
Restrictions For Research Use only

Publications
Application Details Images Alternatives back to top

Opferman, Letai, Beard et al.: "Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1." in: Nature, Vol. 426, Issue 6967, pp. 671-6, 2003 (PubMed).

Alternatives
Application Details Publications Images back to top

Alternatives for antigen "Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1)", type "Antibodies"
Hosts Rabbit (92), Mouse (30), Goat (3)
Reactivities Human (119), Mouse (Murine) (51), Rat (Rattus) (39), Sheep (Ovine) (18), Dog (Canine) (12), Cow (Bovine) (9), Cat (Feline) (7), Horse (Equine) (5), Chicken (4), Monkey (1), Pig (Porcine) (1), Rabbit (1)
Applications Western Blotting (WB) (94), ELISA (49), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (39), Immunofluorescence (IF) (36), Immunoprecipitation (IP) (26), Immunohistochemistry (IHC) (20), Immunocytochemistry (ICC) (14), Immunohistochemistry (Fixed) (IHC (fx)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (4), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes Internal Region (9), AA 121-139 (7), C-Term (5), pThr163,pSer159 (4), N-Term (3), AA 1-327 (2), BH3 Domain (2), Center (1), Isoform 1 (1), Middle Region (1), pSer159 (1), pThr759,pThr758,pSer756 (1)