Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14) antibody

Antigen: Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14)

Synonyms: TR2, ATAR, HVEA, HVEM, LIGHTR, MGC108903, TNFRSF14

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN185517

Additional Information

Alternative name: HVEM / TR2

Gene ID: 8764

Immunogen: C-SVQRKRQEAEGE

Description: All names and symbols: HVEM, TR2, TNFRSF14, tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator), HGNC:11912, ATAR, HVEA, LIGHTR, CD40-like protein precursor, herpesvirus entry mediator, herpesvirus entry mediator A, tumor necrosis factor receptor superfamily, member 14, tumor necrosis factor receptor-like gene2. Official Symbol: TNFRSF14. RefSeq number(s): NP_003811.2

Specificity: Human

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:32,000. Western Blot: Approx 30kDa band observed in human thymus and human tonsil lysates (calculated MW of 30.4kDa according to NP_003811.2). Recommended concentration: 0.03-0.1 µg/ml.

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN185517 (0.03µg/ml) staining of human thymus lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Cheung, Humphreys, Potter et al.: "Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, Issue 37, pp. 13218-23, 2005 (PubMed).