Peripheral-Type Benzodiazepine Receptor (TSPO) antibody

Antigen: Peripheral-Type Benzodiazepine Receptor (TSPO)

Synonyms: DBI, IBP, MBR, PBR, BZRP, PKBS, PTBR, mDRC, pk18, Bzrp, Tspo1, Ptbzr, PTBZR02, RATPTBZR02, LOC732875, LOC100136652, LOC100280949

Clonality: Polyclonal

Host: Goat

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN185697

Additional Information

Alternative name: TSPO / PBR (isoform)

Gene ID: 706

Immunogen: C-RDNHGWRGGRRLPE

Format: Affinity-purified

Description: All names and symbols: TSPO, translocator protein (18kDa) , BZRP, DBI, IBP, MBR, PBR, PKBS, PTBR, mDRC, pk18 , OTTHUMP00000028891, benzodiazapine receptor (peripheral), benzodiazepine peripheral binding site, mitochondrial benzodiazepine receptor, peripheral benzodiazepine rece. Official Symbol: TSPO. RefSeq number(s): NP_000705.2

Specificity: This antibody is expected to recognise one isoform (NP_000705.2) only. Human 169 aa,

Application Details

Application Notes: Peptide ELISA: antibody detection limit dilution 1:128,000. Approx 35kDa band observed in Human Brain lysates (calculated MW of 18.8kDa according to NP_000705.2). The observed molecular weight corresponds to earlier findings in literature with different

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Buffer: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Storage: Aliquot and store at -20°C. Minimize freezing and thawing.

Restrictions: For Research Use only

Images

ABIN185697 (0.1 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Publications

Publications: Papadopoulos, Baraldi, Guilarte et al.: "Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function." in: Trends in pharmacological sciences, Vol. 27, Issue 8, pp. 402-9, 2006 (PubMed).