TSPO antibody (AA 1-50)

Catalog No. ABIN7269228

Product Details anti-TSPO Antibody

Target: TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPO antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: PBR/TSPO Rabbit pAb

Sequence: MAPPWVPAMG FTLAPSLGCF VGSRFVHGEG LRWYAGLQKP SWHPPHWVLG

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-50 of human PBR/PBR/TSPO (NP_000705.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TSPO

Target: TSPO (Peripheral-Type Benzodiazepine Receptor (TSPO))

Alternative Name: TSPO (TSPO Products)

Synonyms: LOC732875 antibody, LOC100136652 antibody, LOC100280949 antibody, BZRP antibody, TSPO antibody, Bzrp antibody, IBP antibody, PBR antibody, Tspo1 antibody, MBR antibody, PTBZR02 antibody, Ptbzr antibody, RATPTBZR02 antibody, BPBS antibody, DBI antibody, PBS antibody, PKBS antibody, PTBR antibody, mDRC antibody, pk18 antibody, peripheral-type benzodiazepine receptor antibody, Peripheral-type benzodiazepine receptor antibody, putative peripheral-type benzodiazepine receptor antibody, translocator protein antibody, translocator protein homolog antibody, hypothetical protein antibody, LOC732875 antibody, MAV_3896 antibody, xccb100_2086 antibody, Smp_102510 antibody, Sros_1911 antibody, tspo antibody, LOC100280949 antibody, PGTG_16395 antibody, TSPO antibody, Tspo antibody

Background: Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by this gene interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported, one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.,TSPO,BPBS,BZRP,DBI,IBP,MBR,PBR,PBS,PKBS,PTBR,mDRC,pk18,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Calcium Signaling,Cardiovascular,Lipids,TSPO

Molecular Weight: 10kDa/18kDa

Gene ID: 706

UniProt: P30536

Pathways: Cellular Response to Molecule of Bacterial Origin