Peripheral-Type Benzodiazepine Receptor (TSPO) antibody

Details for Product No. ABIN6944450
Antigen
  • LOC732875
  • LOC100136652
  • LOC100280949
  • BZRP
  • TSPO
  • Bzrp
  • IBP
  • PBR
  • Tspo1
  • MBR
  • PTBZR02
  • Ptbzr
  • RATPTBZR02
  • BPBS
  • DBI
  • PBS
  • PKBS
  • PTBR
  • mDRC
  • pk18
  • peripheral-type benzodiazepine receptor
  • Peripheral-type benzodiazepine receptor
  • putative peripheral-type benzodiazepine receptor
  • translocator protein
  • translocator protein homolog
  • hypothetical protein
  • LOC732875
  • MAV_3896
  • xccb100_2086
  • Smp_102510
  • Sros_1911
  • tspo
  • LOC100280949
  • PGTG_16395
  • TSPO
  • Tspo
Reactivity
Human, Mouse (Murine)
52
31
8
Host
Rabbit
45
9
8
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
4
2
2
2
2
2
2
2
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Western Blotting (WB)
48
21
19
8
5
5
3
3
3
2
2
Options
Immunogen Human PBP between 50-150 amino acids
Clone 1D4
Isotype IgG
Purification Purified by Protein A.
Antigen
Alternative Name PBR (TSPO Antibody Abstract)
Background

Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism (PubMed:24814875), but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Was initially identified as peripheral-type benzodiazepine receptor, can also bind isoquinoline carboxamides (PubMed:1847678).


Synonyms: Translocator protein, Mitochondrial benzodiazepine receptor, PKBS, Peripheral-type benzodiazepine receptor, PBR, TSPO
Gene ID 706
UniProt P30536
Pathways Cellular Response to Molecule of Bacterial Origin
Application Notes WB(1:300-1000), FCM(1:20-100), IF(ICC)(1:50-200), IHC()
Restrictions For Research Use only
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
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