Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody

Details for Product No. ABIN185733
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms C7orf22, OSM, BC029157, malcavernin, CCM2
Epitope
Internal Region
(4), (3), (2), (1)
Reactivity
Human
(39), (14), (13), (12), (2)
Host
Goat
(19), (19), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Methode Type Peptide ELISA
Application
ELISA, Western Blotting (WB)
(32), (19), (10), (6), (4), (4), (2), (2)
Pubmed 1 reference available
Catalog no. ABIN185733
Quantity 100 µg
Price
374.27 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Available

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide with sequence C-KGEKSRDKKAHEK, from the internal region of the protein sequence according to NP_001025006.1, NP_113631.1, NP_001161407.1.
Specificity This antibody is expected to recognize isoform 1 (NP_001025006.1), isoform 2 (NP_113631.1) and isoform 4 (NP_001161407.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name CCM2
Background Synonyms: CCM2, cerebral cavernous malformation 2, C7orf22, MGC4067, MGC4607, MGC74868, PP10187
Gene ID 83605, 216527
NCBI Accession NP_001025006.1, NP_113631.1, NP_001161407.1
Research Area Neurology
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 48 kDa band observed in Human Heart lysates (calculated MW of 48.8 kDa according to NP_113631.1). Recommended concentration: 0.03-0.1 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
anti-Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody ABIN185733 (0.03µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
General Zawistowski, Stalheim, Uhlik et al.: "CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis." in: Human molecular genetics, Vol. 14, Issue 17, pp. 2521-31, 2005 (PubMed).

Hosts (19), (19), (4)
Reactivities (39), (14), (13), (12), (2)
Applications (32), (19), (10), (6), (4), (4), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top