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CCM2 antibody (Cerebral Cavernous Malformation 2) (Internal Region)

Details for Product anti-CCM2 Antibody No. ABIN185733, Supplier: Login to see
Antigen
  • malcavernin
  • CCM2
  • C7orf22
  • OSM
  • BC029157
Epitope
Internal Region
12
5
2
2
1
1
1
Reactivity
Human
59
9
9
3
2
1
1
1
1
1
Host
Goat
32
15
12
Clonality
Polyclonal
Conjugate
This CCM2 antibody is un-conjugated
1
1
1
1
1
1
1
Methode Type
Peptide ELISA
Application
ELISA, Western Blotting (WB)
53
26
13
8
3
2
Supplier
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Immunogen Peptide with sequence C-KGEKSRDKKAHEK, from the internal region of the protein sequence according to NP_001025006.1, NP_113631.1, NP_001161407.1.
Blocking Peptide Blocking peptide for this product available: ABIN369275
Specificity This antibody is expected to recognize isoform 1 (NP_001025006.1), isoform 2 (NP_113631.1) and isoform 4 (NP_001161407.1).
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine)
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Alternative Name CCM2 (CCM2 Antibody Abstract)
Background Synonyms: CCM2, cerebral cavernous malformation 2, C7orf22, MGC4067, MGC4607, MGC74868, PP10187
Gene ID 83605, 216527
NCBI Accession NP_001025006, NP_113631, NP_001161407
Research Area Neurology
Pathways
Application Notes ELISA: antibody detection limit dilution 1:128000.
Western blot: Approx 48 kDa band observed in Human Heart lysates (calculated MW of 48.8 kDa according to NP_113631.1). Recommended concentration: 0.03-0.1 µg/mL.
Restrictions For Research Use only
Format Liquid
Buffer Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20 °C.
Supplier Images
 image for anti-CCM2 antibody (Cerebral Cavernous Malformation 2) (Internal Region) (ABIN185733) ABIN185733 (0.03µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). ...
Background publications Zawistowski, Stalheim, Uhlik et al.: "CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis." in: Human molecular genetics, Vol. 14, Issue 17, pp. 2521-31, 2005 (PubMed).