Desmoglein 2 antibody

Catalog No. ABIN187348

Product Details anti-Desmoglein 2 Antibody

Target: Desmoglein 2 (DSG2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Desmoglein 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Specificity: The antibody reacts with the 165 kDa desmoglein 2 protein. Furthermore it does NOT cross-react with desmoglein 1 or desmolglein 3. Clone 6D8 does NOT inhibit the biological activity of desmoglein 2. Species Reactivity: Human. NOT suitable for rat tissues. Others not tested.

Sterility: 0.2 μm filtered

Clone: 6D8

Isotype: IgG1

Application Details

Application Notes: Immunofluorescence: Use at a 1:10 dilution. Immunoprecipitation Western blotting: Use at a 1:10 dilution. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 mL at 100 µg/mL of 0.2 µm filtered antibody solution in PBS, containing 0.02% sodium azide and 0.1% protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Desmoglein 2

Target: Desmoglein 2 (DSG2)

Alternative Name: Desmoglein-2 (DSG2 Products)

Synonyms: DSG2 antibody, dsc antibody, dsga antibody, si:dkeyp-51f12.6 antibody, wu:fj23f02 antibody, ARVC10 antibody, ARVD10 antibody, CDHF5 antibody, CMD1BB antibody, HDGC antibody, AA408168 antibody, D18Ertd293e antibody, desmoglein 2 antibody, desmoglein 2, tandem duplicate 1 antibody, DSG2 antibody, dsg2.1 antibody, dsg2 antibody, Dsg2 antibody

Background: Desmoglein 2 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 2 is synthesized in the basal layers, depending on the certain types of epidermis.

Pathways: Cell-Cell Junction Organization