BAX antibody

Catalog No. ABIN187418

The Mouse Monoclonal anti-BAX antibody is suitable to detect BAX in samples from Human. It has been validated for WB, IHC (p) and IHC (fro).

Quick Overview for BAX antibody (ABIN187418)

Target: BAX (BCL2-Associated X Protein (BAX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAX antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 2D2

Product Details anti-BAX Antibody

Specificity: Reacts with human Bax. Species Reactivity: Human. Others not tested.

Sterility: 0.2 μm filtered

Immunogen: Synthetic peptide corresponding to aa 3-16 of the human Bax protein.

Isotype: IgG1

Application Details

Application Notes: Western blotting: Use at a 1:10,000 dilution. The optimal dilution for a specific application should be determined by the researcher.

Restrictions: For Research Use only

Handling

Buffer: Purified antibody (1 mg/mL) from ascites fluid, 0.2 µm sterile filtered solution in PBS with 0.08% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for BAX

Target: BAX (BCL2-Associated X Protein (BAX))

Alternative Name: Bax

Background: Bax is a Bcl-2 homolog and a member of the Bcl-2 family of oncoproteins. Bax expression is associated with cell death regulation. The ratio of Bax to other Bcl-2 family members is believed to regulate apoptosis.

Pathways: p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response