BAX antibody (N-Term)

Catalog No. ABIN6254209

This Goat Polyclonal antibody specifically detects BAX in WB, IF, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat, Monkey, Pig, Cow, Rabbit, Chicken, Dog, Sheep, Hamster, Horse, Guinea Pig, Avian, Cat, Donkey and Goat.

Quick Overview for BAX antibody (N-Term) (ABIN6254209)

Target: BAX (BCL2-Associated X Protein (BAX))

Reactivity: Human, Mouse, Rat, Monkey, Pig, Cow, Rabbit, Chicken, Dog, Sheep, Hamster, Horse, Guinea Pig, Avian, Cat, Donkey, Goat

Host: Goat

Clonality: Polyclonal

Conjugate: This BAX antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BAX Antibody

Binding Specificity: N-Term

Purpose: Anti-BAX

Sequence: MDGSGEQPRG GGPTSSEQIM KTGALLLQGF IQDRAGRMGG EAPELALDPV PQDASTKKLS ECLKRIGDEL DSNMELQRMI AAVDTDSPRE VFF

Specificity: Detects a band of approximately 21 kDa by Western blot in the following cell lysate: hCat, At-T20, MDA-MB-231, H69 and HUH.

Characteristics: BCL2-associated X protein

Purification: Epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 90 aa to the N-terminus of human BAX produced in E. coli.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:5,000, IF:1:50-1:250, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000

Restrictions: For Research Use only

Handling

Buffer: PBS, 20 % glycerol and 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for BAX

Target: BAX (BCL2-Associated X Protein (BAX))

Alternative Name: BAX

Background:

Goat polyclonal antibody to BAX. This protein belongs to the BCL2 protein family that act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The expression of BAX gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis.

BCL2-associated X protein antibody.

Pathways: p53 Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response