This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ASB9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASB9.
ASB9
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
HRP
Application Notes
WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Expiry Date
6 months
Fei, Gu, Fan, Yang, Li, Zhang, Gong, Mao, Ji: "Crystal structure of Human ASB9-2 and substrate-recognition of CKB." in: The protein journal, Vol. 31, Issue 4, pp. 275-84, (2012) (PubMed).
Kwon, Kim, Rhee, Park, Kim, Kim, Lee, Kwon: "ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial function." in: BMC biology, Vol. 8, pp. 23, (2010) (PubMed).
Target
ASB9
(Ankyrin Repeat and SOCS Box Containing 9 (ASB9))
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes at least two forms of creatine kinase, CKB and CKMT1A.