Desmocollin 2 antibody (AA 480-676)

Catalog No. ABIN1886508

Product Details anti-Desmocollin 2 Antibody

Target: Desmocollin 2 (DSC2)

Binding Specificity: AA 480-676

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmocollin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 480 and 676 of Desmocollin 2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Desmocollin 2

Target: Desmocollin 2 (DSC2)

Alternative Name: Desmocollin 2 (DSC2 Products)

Synonyms: ARVD11 antibody, CDHF2 antibody, DG2 antibody, DGII/III antibody, DSC3 antibody, AW228162 antibody, Dsc2a antibody, Dsc2b antibody, DSC2 antibody, desmocollin 2 antibody, DSC2 antibody, Dsc2 antibody

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily.These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation.The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.Alternative splicing results in two transcript variants encoding distinct isoforms.[provided by RefSeq]

Molecular Weight: 94 kDa

Gene ID: 1824

NCBI Accession: NM_004949, NP_004940