PPAPDC2
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
FITC
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
PPAPDC2
(Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2))
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity.PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation.PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts.It is widely expressed in human tissues.Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase. Synonyms: Phosphatidic acid phosphatase type 2 domain containing 2, PSD