AIM (C-Term) antibody

Catalog No. ABIN1886929

Product Details

Target: AIM

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 13 amino acid peptide near the carboxy terminus of human AIM.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details

Target: AIM

Synonyms: 5830438K24Rik antibody, AI452015 antibody, AIM antibody, VEA antibody, BL-AC/P26 antibody, CLEC2C antibody, EA1 antibody, GP32/28 antibody, MLR-3 antibody, CD69 antigen antibody, CD69 molecule antibody, Cd69 antibody, CD69 antibody

Background: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5.It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection.AIM was also shown to support macrophage survival and enhance their phagocytic function.More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C.parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.
Synonyms: Apoptosis inhibitor of macrophages, API6, SP alpha, CD5L