LIPE antibody (C-Term)

Catalog No. ABIN1886949

Product Details anti-LIPE Antibody

Target: LIPE (Lipase, Hormone-Sensitive (LIPE))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIPE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide from near the carboxy terminus of human lipe.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for LIPE

Target: LIPE (Lipase, Hormone-Sensitive (LIPE))

Alternative Name: Lipe (LIPE Products)

Synonyms: ADAP antibody, PRO0823 antibody, SLAP-130 antibody, HSL antibody, LHS antibody, hsl antibody, LIPE antibody, 4933403G17Rik antibody, A antibody, CG11055 antibody, Dmel\CG11055 antibody, anon-56Ea antibody, dHSL antibody, lipe antibody, si:dkey-3n22.7 antibody, FYN binding protein 1 antibody, lipase E, hormone sensitive type antibody, lipase, hormone-sensitive antibody, lipase, hormone-sensitive L homeolog antibody, lipase, hormone sensitive antibody, Hormone-sensitive lipase antibody, lipase, hormone-sensitive a antibody, FYB1 antibody, LIPE antibody, Lipe antibody, lipe antibody, lipe.L antibody, Hsl antibody, lipea antibody

Background: Although initially described as an adipocyte-specific triacylglycerol lipase, lipe (also known as hormone-specific lipase or HSL) is expressed in multiple tissues and cell lines.It plays multiple roles in lipid metabolism, including hormone-stimulated lipolysis in adipose tissue and the hydrolysis of cholesterol esters.Lipe is expressed as a long and a short form, generated by use of alternative translational start codons.The long form is expressed in steroidogenic tissues such as testis, where it converts cholesterol esters to free cholesterol for steroid hormone production.The short form is expressed in adipose tissue, among others, where it hydrolyzes stored triglycerides to free fatty acids.Recently, it was observed that the lack of lipe in genetically obese leptin-null mice inhibited obesity and adipogenesis, suggesting that lipe plays a major role in adipocyte proliferation.
Synonyms: hormone-sensitive lipase, HSL

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process, Lipid Metabolism