KCNK12 antibody (C-Term)

Catalog No. ABIN1886980

Product Details anti-KCNK12 Antibody

Target: KCNK12 (Potassium Channel, Subfamily K, Member 12 (KCNK12))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): KCNK12 antibody is predicted to not cross-react with other KCNK protein family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the carboxy terminus of human KCNK12.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for KCNK12

Target: KCNK12 (Potassium Channel, Subfamily K, Member 12 (KCNK12))

Alternative Name: KCNK12 (KCNK12 Products)

Synonyms: KCNK12 antibody, K2p12.1 antibody, THIK-2 antibody, THIK2 antibody, mntk1 antibody, potassium two pore domain channel subfamily K member 12 antibody, potassium channel, subfamily K, member 12 antibody, KCNK12 antibody, Kcnk12 antibody

Background: KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily.The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity.Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells.KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle.KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.
Synonyms: Potassium channel subfamily K member 12, Tandem pore domain halothane-inhibited potassium channel 2, THIK2

NCBI Accession: NP_071338