CUEDC1 antibody (C-Term)

Catalog No. ABIN1887133

Product Details anti-CUEDC1 Antibody

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CUEDC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity (Details): CUEDC1 antibody will not cross-react with CUEDC2.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human CUEDC1.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CUEDC1

Target: CUEDC1 (CUE Domain Containing 1 (CUEDC1))

Alternative Name: CUEDC1 (CUEDC1 Products)

Synonyms: AI841487 antibody, C330016O16Rik antibody, RGD1304861 antibody, CUEDC1 antibody, zgc:153423 antibody, zgc:162271 antibody, CUE domain containing 1 antibody, CUE domain containing 1 L homeolog antibody, CUE domain containing 1a antibody, CUE domain containing 1b antibody, CUEDC1 antibody, Cuedc1 antibody, cuedc1.L antibody, cuedc1 antibody, cuedc1a antibody, cuedc1b antibody

Background: The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, ~40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation.CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found.CUEDC1 (CUE domain-containing protein 1) is a 386 amino acid protein that contains one CUE domain, suggesting a possible role in protein trafficking and degradation pathways.Two isoforms of CUEDC1 exist due to alternative splicing events.Defects in the gene encoding CUEDC1 may be associated with early stage cervical cancer, implicating CUEDC1 as a potential tumor marker.
Synonyms: CUE Domain-Containing Protein 1