HILPDA antibody (C-Term)

Catalog No. ABIN1887137

Product Details anti-HILPDA Antibody

Target: HILPDA (Hypoxia Inducible Lipid Droplet-Associated (HILPDA))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HILPDA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): At least two isoforms of HIG2 are known to exist, this antibody will detect both isoforms. HIG2 antibody is predicted to not cross-react with HIG1

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human HIG2.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for HILPDA

Target: HILPDA (Hypoxia Inducible Lipid Droplet-Associated (HILPDA))

Alternative Name: HIG2 (HILPDA Products)

Synonyms: 2310016C08Rik antibody, AW049004 antibody, Hig2 antibody, C7orf68 antibody, HIG-2 antibody, HIG2 antibody, hypoxia inducible lipid droplet associated antibody, Hilpda antibody, HILPDA antibody

Background: HIG1 and HIG2 (Hypoxia-inducible gene 1 and 2, respectively) are known to be induced by hypoxic conditions.HIG2 is induced by hypoxia and by glucose deprivation in cultured cells.In addition, tumor xenografts derived from human cervical cancer cells display increased expression of HIG1 and HIG2 when they are deprived of oxygen.Unlike HIG2, which is ubiquitously expressed and might be an activator and target of the canonical Wnt pathway, the function and the mechanisms underlying its regulation of HIG1 still remained unknown.The putative link between hypoxia and an oncogenic signaling pathway might play an important role in tumorigenesis.
Synonyms: Hypoxia-inducible gene 2 protein, HIG-2

NCBI Accession: NP_001092256