IRF4 antibody (C-Term)

Catalog No. ABIN1887138

Product Details anti-IRF4 Antibody

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity (Details): IRF4 antibody is predicted to not cross-react with other IRF protein family members. IRF4 often migrates at a higher than predicted molecular weight in SDS-PAGE.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human IRF4.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for IRF4

Target: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Alternative Name: IRF4 (IRF4 Products)

Synonyms: LSIRF antibody, MUM1 antibody, NF-EM5 antibody, AI385587 antibody, IRF-4 antibody, Spip antibody, IRF4 antibody, si:ch73-170d1.2 antibody, irf4 antibody, interferon regulatory factor 4 antibody, interferon regulatory factor 4a antibody, Interferon regulatory factor 4 antibody, PWWP domain-containing protein MUM1 antibody, IRF4 antibody, Irf4 antibody, irf4a antibody, irf4 antibody, LOC612320 antibody, LOC100068881 antibody

Background: Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms.During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes.Another member, IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes.IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes.IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR signaling.
Synonyms: Interferon regulatory factor 4, MUM1, LSIRF

NCBI Accession: NP_002451

Pathways: Chromatin Binding