LRFN5
Reactivity: Mammalian
IHC, ISt
Host: Mouse
Monoclonal
N140A-12
unconjugated
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS containing 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice
Avoid freezing and thawing repeatly.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
LRFN5
(Leucine Rich Repeat and Fibronectin Type III Domain Containing 5 (LRFN5))
C14orf146 antibody, FIGLER8 antibody, SALM5 antibody, AI427653 antibody, AI604817 antibody, C130061B21 antibody, mKIAA4208 antibody, leucine rich repeat and fibronectin type III domain containing 5 antibody, LRFN5 antibody, Lrfn5 antibody
Background
LRFN5 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues.LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins.Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells.LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery.It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system. Synonyms: Leucine-rich repeat and fibronectin typeIII domain-containing protein 5, synaptic adhesion-like molecule 5, SALM5, FIGLER8