BCAP31 antibody (C-Term)

Catalog No. ABIN1887162

Product Details anti-BCAP31 Antibody

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAP31 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide from near the carboxy terminus of human BAP31.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for BCAP31

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Alternative Name: BAP31 (BCAP31 Products)

Synonyms: 6c6-ag antibody, bap31 antibody, cdm antibody, dxs1357e antibody, BCAP31 antibody, Bap31 antibody, 6C6-AG antibody, BAP31 antibody, CDM antibody, DXS1357E antibody, CALD1 antibody, caldesmon antibody, si:bz30i22.4 antibody, si:rp71-30i22.4 antibody, zgc:56389 antibody, B-cell receptor associated protein 31 antibody, receptor-associated protein antibody, lipopeptide mating pheromone precursor bap3-1 antibody, B cell receptor associated protein 31 antibody, B-cell receptor-associated protein 31 antibody, B-cell receptor associated protein 31 L homeolog antibody, bcap31 antibody, BAP31 antibody, bap3-1 antibody, BCAP31 antibody, Bcap31 antibody, bcap31.L antibody

Background: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family.These two proteins are highly homologous and can form homo- and heterodimers.Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18.It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria.Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis.The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death.
Synonyms: BAP31, B cell receptor-associated protein 31 BCR associated protein 31

NCBI Accession: NP_005736

Pathways: Positive Regulation of Endopeptidase Activity