CLIP1 antibody (C-Term)

Catalog No. ABIN1887163

Product Details anti-CLIP1 Antibody

Target: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide from near the carboxy terminus of human CLIP170.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for CLIP1

Target: CLIP1 (CAP-GLY Domain Containing Linker Protein 1 (CLIP1))

Alternative Name: CLIP170 (CLIP1 Products)

Synonyms: RSN antibody, CLIP1 antibody, clip170 antibody, clip-170 antibody, CLIP antibody, CLIP-170 antibody, CLIP170 antibody, CYLN1 antibody, 1110007I12Rik antibody, 4631429H07Rik antibody, AV017631 antibody, C81039 antibody, Clip50 antibody, Rsn antibody, mKIAA4046 antibody, restin antibody, CAP-Gly domain containing linker protein 1 antibody, CAP-Gly domain-containing linker protein 1 antibody, CAP-Gly domain containing linker protein 1 L homeolog antibody, CAP-GLY domain containing linker protein 1b antibody, CAP-GLY domain containing linker protein 1 antibody, CLIP1 antibody, LOC100075022 antibody, clip1 antibody, clip1.L antibody, clip1b antibody, Clip1 antibody

Background: CLIP170 was initially identified as a new type of intermediate filament associated protein that is highly expressed in Reed-Sternberg cells, the tumoral cells diagnostic for Hodgkin's disease.Later experiments showed that it is located at microtubule plus ends and is required for the binding of endocytic carrier vesicles.CLIP170 has also been suggested to act with LIS1, a protein implicated in brain development, to regulate dynein/dynactin binding microtubules.Other studies suggest that CLIP170 can influence the formation of lamellipodia and cell invasion by invasive breast cancer cells by regulating the release of kinesin and IQGAP1 from a complex of those proteins, CLIP170 and Rac1.At least two isoforms of CLIP170 are known to exist.
Synonyms: CAP-Gly domain-containing linker protein 1, CLIP, CYLN1, Restin, RSN

NCBI Accession: NP_002947

Pathways: Microtubule Dynamics